Search on: LUTEINIZING HORMONE, BETA SUBUNIT 
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Descriptor English:   Luteinizing Hormone, beta Subunit 
Descriptor Spanish:   Hormona Luteinizante de Subunidad beta 
Descriptor Portuguese:   Hormônio Luteinizante Subunidade beta 
Synonyms English:   LH-beta
Luteinizing Hormone, beta Chain
Luteinizing Hormone, beta Polypeptide Chain
Lutropin-beta
LH beta
Lutropin beta
ICSH, beta Subunit
LH, beta Subunit
Lutropin, beta Subunit  
Tree Number:   D06.472.699.322.576.463.500
D06.472.699.631.525.343.463.500
D12.644.548.691.525.343.463.500
Definition English:   The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility. 
History Note English:   2003; use LUTEINIZING HORMONE, BETA SUBUNIT (NM) 1983-2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   37314 
Unique Identifier:   D037101 

Occurrence in VHL:
 

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